Wikipedia says that,
The brain shiver effect appears to be almost unique to those antidepressant chemicals that have an extremely short half-life in the body; that is, they are quick to disappear completely. This attribute of abruptness leaves the brain a relatively short time to adapt to a major neurochemical change when the medication is stopped, and the symptoms may be caused by the brain's readjustment. There is no evidence that the shivers present any danger to the patient experiencing them.
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